Once you establish sales tax nexus in a jurisdiction you are required to register with that jurisdiction to collect and remit sales taxes. Anrok will show you where you are approaching economic nexus, at which point it may be a good time to begin the registration process as some states can take up to 6 weeks to process a registration.
You can find where you are exposed or approaching nexus in the Nexus map on the Dashboard or in the Action required tab on the Jurisdictions page.
In addition, regular check-ins with payroll are important to know whether you have an employee in a new state and need to register there.